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Dave Plummer is a programmer, former Microsoft software engineer (Windows 95, NT, XP), creator of Task Manager, author of two books on autism, and host of the Dave’s Garage YouTube channel, where he shares stories from his career, insights on software development, and deep dives into technology. https://lexfridman.com/sponsors/ep479-sc CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://x.com/davepl1968 https://www.youtube.com/@DavesGarage https://www.youtube.com/@davepl https://github.com/PlummersSoftwareLLC https://amzn.to/41qd5IB SPONSORS: UPLIFT Desk: Standing desks and office ergonomics. https://upliftdesk.com/lex ZocDoc: App that helps patients find healthcare providers. https://zocdoc.com/lex Fin: AI agent for customer service. https://fin.ai/le

In this episode, Dr. Liam Holt from NYU Langone Health joins us to uncover the hidden world of LINE-1, a viral-like DNA element that makes up a massive part of our genome. We explore how this ancient stowaway shaped human evolution, why it might be fueling aging, inflammation, and cancer, and explore whether science can turn it from a threat into a tool. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Scott Horton is the director of the Libertarian Institute, editorial director of Antiwar.com, host of The Scott Horton Show, co-host of Provoked, and for the past three decades a staunch critic of U.S. military interventionism. https://lexfridman.com/sponsors/ep478-sc CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://lexfridman.com/scott-horton-links-and-notes/ https://x.com/scotthortonshow https://youtube.com/@scotthortonshow https://youtube.com/@Provoked_Show https://scotthortonshow.com/ https://scotthorton.org/ https://amzn.to/3T9Qg7y https://libertarianinstitute.org/ https://antiwar.com/ SPONSORS: Allio Capital: AI-powered investment app that uses global macroeconomic trends. https://alliocapital.com/ Hampton: Community for high-growth founders a

Today, we’re joined by Dr. Shu Yang, a pioneering materials scientist at the University of Pennsylvania and one of National Geographic’s Extraordinary Changemakers. From elephant skin to snail mucus, Dr. Yang draws inspiration from nature to create shape-shifting, sustainable materials that could transform everything from medicine to construction. Stay tuned as we explore the science behind smart surfaces, kirigami geometry, carbon-sequestering concrete, and the curiosity that drives them all. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Keyu Jin is an economist specializing in China’s economy, international macroeconomics, global trade imbalances, and financial policy. She is the author of The New China Playbook: Beyond Socialism and Capitalism. https://lexfridman.com/sponsors/ep477-sc Transcript: https://lexfridman.com/keyu-jin-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://x.com/KeyuJin https://keyujin.com/ https://amzn.to/4lpgmyK SPONSORS: Allio Capital: AI-powered investment app that uses global macroeconomic trends. https://alliocapital.com/ UPLIFT Desk: Standing desks and office ergonomics. https://upliftdesk.com/lex Hampton: Community for high-growth founders and CEOs. https://joinhampton.com/lex Lindy: No-code AI agent builder. https://go.lindy.ai/lex LMNT: Zer

Jack Weatherford is an anthropologist and historian specializing in Genghis Khan and the Mongol Empire. https://lexfridman.com/sponsors/ep476-sc Transcript: https://lexfridman.com/jack-weatherford-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://amzn.to/3ISziZr https://amzn.to/4l45LsY https://amzn.to/4l22uud https://amzn.to/4fpOQA4 https://amzn.to/40JEll1 SPONSORS: Allio Capital: AI-powered investment app that uses global macroeconomic trends. https://alliocapital.com/ ZocDoc: App that helps patients find healthcare providers. https://zocdoc.com/lex Fin: AI agent for customer service. https://fin.ai/lex Oracle: Cloud infrastructure. https://oracle.com/lex Shopify: Sell stuff online. https://shopify.com/lex MasterClass: Online classes from

In this episode, we are joined by Will Ashford-Brown, Director at the Heligan Strategic Insights team, and a leading expert on AI, autonomous systems, and modern warfare. From drone swarms and digital deception to the ethics of kill-chain automation, we explore how emerging technologies are reshaping the battlefield — and what that means for the world. Let’s dive in. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. https://lexfridman.com/sponsors/ep475-sc Transcript: https://lexfridman.com/demis-hassabis-2-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://x.com/demishassabis https://x.com/GoogleDeepMind https://instagram.com/GoogleDeepMind https://deepmind.google/ https://gemini.google.com/ https://isomorphiclabs.com/ https://amzn.to/4lOXJ81 https://amzn.to/3AhUP7z SPONSORS: Hampton: Community for high-growth founders and CEOs. https://joinhampton.com/lex Fin: AI agent for customer service. https://fin.ai/lex Shopify: Sell stuff online. https://shopify.com/lex LMNT: Zero-sugar electrolyte drink mix. https://drinkLM

In this episode of Lexicon, we speak with Dr. Scott Miller, Director of Technology at NextFlex, to explore how hybrid electronics are revolutionizing manufacturing. From aerospace to healthcare, Scott explains how printed and flexible electronics are enabling smarter, more sustainable, and more resilient systems while helping bring manufacturing back home. Whether you’re into next-gen tech, supply chains, or the future of wearables, this conversation connects the circuits. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

David Heinemeier Hansson (aka DHH) is a legendary programmer, creator of Ruby on Rails, co-owner & CTO of 37signals that created Basecamp, HEY, & ONCE, and is a NYT-best-selling author (with Jason Fried) of 4 books: REWORK, REMOTE, Getting Real, and It Doesn’t Have To Be Crazy At Work. He is also a race car driver, including a class-winning performance at the 24 hour Le Mans race. https://lexfridman.com/sponsors/ep474-sc Transcript: https://lexfridman.com/dhh-david-heinemeier-hansson-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://x.com/dhh https://dhh.dk/ https://rubyonrails.org/ https://37signals.com/ DHH’s books: https://amzn.to/44rSKob https://amzn.to/44GFJ91 https://amzn.to/46bzuwx https://amzn.to/4kzoMDg SPONSORS: UPLIFT Desk: Stan

In this episode, we sit down with Justin Graham and Jake Dein from Barge Design Solutions to explore the real-world challenges of implementing AI in engineering. From avoiding the "streetlight effect" to saving clients millions through more intelligent data integration, they share hard-earned insights on why clean, connected data, not just flashy tools, is the key to meaningful innovation. If you're thinking about AI, this episode will show you where to start. Level up your knowledge with IE+! Subscribe today to access exclusive premium articles enriched with expert insights and enjoy members-only technical newsletters designed to keep you ahead in technology and science.

Debate on Iran war between Scott Horton and Mark Dubowitz. Scott Horton is the author and director of the Libertarian Institute, editorial director of Antiwar.com, host of The Scott Horton Show, and for the past three decades, a staunch critic of U.S. foreign policy and military interventionism. Mark Dubowitz is the chief executive of the Foundation for Defense of Democracies, host of the Iran Breakdown podcast, and a leading expert on Iran and its nuclear program for over 20 years. This debate was recorded on Tuesday, June 24, after the Iran-Israel ceasefire was declared. https://lexfridman.com/sponsors/ep473-sc Transcript: https://lexfridman.com/iran-war-debate-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://x.com/mdubowitz https://you

In this episode of Lexicon, we sit down with Graeme Purdy, CEO and co-founder of Ilika Technologies — a trailblazer in solid-state battery innovation. With EV adoption surging and energy storage tech evolving fast, Graeme shares how Ilika’s Goliath program redefines what’s possible for electric vehicles and beyond. Join us as we explore battery safety, manufacturing at scale, Europe’s role in the global battery race, and why solid-state might be the leap we’ve been waiting for. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Terence Tao is widely considered to be one of the greatest mathematicians in history. He won the Fields Medal and the Breakthrough Prize in Mathematics, and has contributed to a wide range of fields from fluid dynamics with Navier-Stokes equations to mathematical physics & quantum mechanics, prime numbers & analytics number theory, harmonic analysis, compressed sensing, random matrix theory, combinatorics, and progress on many of the hardest problems in the history of mathematics. https://lexfridman.com/sponsors/ep472-sc Transcript: https://lexfridman.com/terence-tao-transcript CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://terrytao.wordpress.com/ https://www.youtube.com/@TerenceTao27 https://amzn.to/43H9Aiq SPONSORS: Notion: Note-taking and team

In this episode, we sit down with Raj Toleti, Chairman and CEO of Andor Health, to explore how AI is transforming virtual care, without replacing the human touch. From reducing clinician burnout to accelerating time-to-treatment, Raj shares how ThinkAndor® is building a more intelligent, more connected healthcare system powered by AI agents that collaborate across every stage of care. If you’re curious about the future of healthcare tech, this conversation is a must-listen. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

In today’s episode, we’re talking to Paul Van Metre, co-founder of ProShop ERP, a manufacturing software platform born out of pure necessity. We delve into why precision machining is the backbone of modern life, how real-time data and going paperless can transform company culture, and what it takes to help small shops punch well above their weight. If you’ve ever wondered how the stuff we rely on actually gets made, this one’s for you. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Today, we're diving into a fascinating conversation with Dr. Illana Ressler, a leading reproductive endocrinologist at Illume Fertility. Join us as we explore the connection between metabolic health and fertility, uncover the science behind conditions like PCOS, and discuss why medications like Ozempic are making waves in reproductive wellness. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

In this episode of Lexicon, we speak with Lin Sun Fa, CEO of Emobi, about the future of EV charging. From AI-driven reliability scores to cybersecurity and digital IDs, Lin shares how Emobi is building the invisible infrastructure powering seamless, secure, and smart electric mobility. Whether you're an EV owner, a tech enthusiast, or just curious about what’s next for connected transport—this one’s for you. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!

Today we’re joined by Matt Casella, President of Richtech Robotics, to explore how AI-driven robots like ADAM are transforming hospitality, healthcare, and beyond. We'll dive into the exciting potential of robots with personality, the human side of automation, and Matt’s vision for a future where humans and robots seamlessly collaborate. Also, don’t forget to subscribe to IE+ for premium insights and exclusive content!